Utilization of Isoflavones with Basic Material of Robusta Coffee Skin with BMD (Bone Marrow Density) Markers in Peri / Post Menopausal Women

Ratna Dewi Puspita Sari, Samsul Bakrie

Abstract


The increase in life expectancy of women in Indonesia, which reaches 72 years of age causes almost a third of her life span lived at the time of menopause. The population of menopausal women in Indonesia will increase with all the effects due to decreased estrogen in the form of climatic complaints and an increased risk of bone loss / osteoporosis. The best choice and is the standard treatment for climatic complaints and osteoporosis is hormonal therapy (Estrogen + Progesterone / Estrogen). WHI in 2004 stated that hormone therapy in menopausal women increases the risk of breast cancer. In Indonesia, phytoestrogens are widely circulated in the market with the category of supplements and have been used by the public to deal with climatic complaints and osteoporosis. This phytoestrogen has not been scientifically proven to be useful for overcoming climatic and osteoporotic complaints in postmenopausal women. Phytoestrogens on the market used as Permi III pills contain Red Clover, Black Cohosh and calcium. Some studies say that phytoestrogens for osteoporosis therapy can be obtained from isoflavones derived from robusta coffee skins. This isoflavone can affect bone mineral density in peri / postmenopausal women. The use of phytoestrogens (isoflavones) from the skin of coffee beans affects peri / postmenopausal women and helps maintain and build bone mass (reduce the occurrence of osteoporosis complaints).

Keywords


Fitoestrogen, menopause, isoflavone, bone density

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References


Abbot NC. Pointing the Bone at Osteoporosis. Orgyn. 2001;Vol.12 No. 3:23-6.

Belchetz PE., Hormonal Treatment of Postmenopausal Women. The New England Journal of Medicine. 1994;Vol. 330 No.15:1062-71.

Brown J P., Josse R G., Brown et. al., 2002 Clinical Practice Guidelines for the Diagnosis and Management of Osteoporosis in Canada. Canadian Mediacal Association Journal. 2002;167.

Raisz L G.,Physiology and Pathophysiology of Bone Remodeling. Clinical Chemestry. 1999;45:1353-1358.

Rachman IA, Berbagai Ragam Pengobatan dan Diagnosis Osteoporosis , Permi. 2002: 20-24.

Cure-cure C, CureRamires P. Hormonal Replacement Therapy for Bone Protection in Multiparous Women: Whwn to initiate it. Am. J. Obstet Gynecol. 2001;184:580-3.

Watts N., Osteoporosis: Methods to Prevent Fraktures in Patiens at High Risk, Postgraduate Medicine. 1994; No.5:73-86.

Wood AJJ, Treatmen of Postmenopausal Osteoporosis, The New England Journal of Medicine. 1999;Vol. 338 No.11:736-46.

Ettiger B, Grady D. The Waning Effect of Postmenopausal Estrogen Therapy on Osteoporosis . The New England Journal of Medicine. 1993;Vol. 329 No.16:1192-1193.




DOI: https://doi.org/10.32539/bji.v5i3.8684

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